@Jon no. Here are the details I remember:
Out of the hundreds of times I ran Lightfinger Estate, I came across the bug 2-3 times.
100% sure last time was in a secret room at room 2. Fairly sure every time it happened was in a secret room, but not 100% on that one.
The only hostile I remember was a barbed demon, but don’t remember the rest of them.
The only ability I can say with 100% certainty that doesn’t work in there is Mass Cure Wounds from the Pirates Scarf. You select the ability and regardless of where you tap, it doesn’t register. I force quit the game several times and it did not clear the issue. The issue is definitely with that room as if it doesn’t recognize any tile as a valid target. Good luck finding that needle in the code, ha.